Entry Information
Rejected
25D0296
Edwin Chan - Life Science and Medicine
King Chow - Life Science and Medicine
43
32
37.5
Simone Leoni
Mr
Male
22/12/1996
Switzerland
Passport
X2621
Swiss
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+41786923939
Schlossstrasse 117
Bern
Switzerland
Life Science and Medicine
Astronomy
I am eager to join the Hong Kong Laureate Forum to contribute to the exchange of ideas among scientists of diverse generations, cultures, and disciplines. As a young scientist, I am passionate about fostering collaboration and believe that networking with peers from different backgrounds is key to advancing research and innovation.
The forum’s emphasis on cooperation between different sectors to promote education in science and technology aligns with my goals of bridging the gap between academia, industry, and society. I am committed to contributing to initiatives that encourage cross-disciplinary collaboration and the growth of science and technology education in Hong Kong.
Joining this forum will provide an invaluable opportunity to learn, share ideas, and actively contribute to a global community of passionate scientists.
Postgraduate (PhD)
Neurovirology
University of Bern
Bern, Switzerland
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First Academic or Research Referee *
Stephen L. Leib
University of Bern
Director of Institute for Infectious Diseases
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Second Academic or Research Referee
Denis Grandgirard
University of Bern
Research assistant
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• Travel grant ECCMID 2023
• Top rated poster ECCMID 2023
• Travel grant ESCMID Global 2024
• Top rated abstract ESCMID Global 2024
Tick-borne encephalitis virus (TBEV) is a neurotropic virus transmitted by ticks, causing inflammation of the brain (encephalitis) in humans. With no specific antiviral treatment currently available, only symptomatic care is provided to affected individuals. My research aims to better understand the neuronal pathomechanism of TBEV infection, focusing on how the virus affects the central nervous system.
To achieve this, I utilize a multi-model approach. In vitro, I work with cell cultures to investigate cellular responses to TBEV. Ex vivo, I use organotypic brain slice cultures to study the virus’s impact on brain tissue in a more complex, 3D context. In vivo, I use Wistar rats to observe the effects of TBEV in a living organism, simulating human infection more closely.
An important goal of my research is to test several antiviral candidates using these models. Since there is currently no specific antiviral treatment for TBEV, identifying potential therapeutics could significantly improve patient outcomes and open new avenues for clinical management of the disease.
Both Sessions